Temi di Ricerca

• • Development of metabolomics pipelines applied to the “One-Health” approach
  • Study of metabolic rewiring in cancer and neurodegenerative models
  • Impact of environmental pollution on human health
  • Biomarker research in complex biological systems

Bibliografia recente di maggior rilevanza

1. Emodin and Aloe-Emodin Reduce Cell Growth and Disrupt Metabolic Plasticity in Human Melanoma Cells. Baldassari F, Bonanomi M, Mallia S, Bonas M, Brivio E, Aramini T, Porro D, Gaglio D. Nutrients. 2025 Mar 22;17(7):1113. doi: 10.3390/nu17071113.
2. 3D Modeling: Insights into the Metabolic Reprogramming of Cholangiocarcinoma Cells. Ciufolini G, Zampieri S, Cesaroni S, Pasquale V, Bonanomi M, Gaglio D, Sacco E, Vanoni M, Pastore M, Marra F, Cicero DO, Raggi C, Petrella G. Cells. 2024 Sep 13;13(18):1536. doi: 10.3390/cells13181536.
3. A Novel Strategy for Glioblastoma Treatment by Natural Bioactive Molecules Showed a Highly Effective Anti-Cancer Potential. Giammona A, Commisso M, Bonanomi M, Remedia S, Avesani L, Porro D, Gaglio D, Bertoli G, Lo Dico A. Nutrients. 2024 Jul 23;16(15):2389. doi: 10.3390/nu16152389.
4. Glycolytic activity and in vitro effect of the pyruvate kinase activator AG-946 in red blood cells from low-risk myelodysplastic syndromes patients: A proof-of-concept study. Fattizzo B, Vercellati C, Marcello A, Patel P, Wind-Rotolo M, Pettine L, Bonanomi M, Gaglio D, Bortolotti M, Leoni C, Fermo E, Bianchi P, Zaninoni A, Passamonti F, Barcellini W. Am J Hematol. 2024 Jun;99(6):1201-1204. doi: 10.1002/ajh.27300.
5. Fusion-fission-mitophagy cycling and metabolic reprogramming coordinate nerve growth factor (NGF)-dependent neuronal differentiation. Goglia I, Węglarz-Tomczak E, Gioia C, Liu Y, Virtuoso A, Bonanomi M, Gaglio D, Salmistraro N, De Luca C, Papa M, Alberghina L, Westerhoff HV, Colangelo AM. FEBS J. 2024 Jul;291(13):2811-2835. doi: 10.1111/febs.17083.
6. Plastic leachate-induced toxicity during sea urchin embryonic development: Insights into the molecular pathways affected by PVC. Paganos P, Ullmann CV, Gaglio D, Bonanomi M, Salmistraro N, Arnone MI, Jimenez-Guri E. Sci Total Environ. 2023 Mar 15;864:160901. doi: 10.1016/j.scitotenv.2022.160901.
7. CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer. Filippone MG, Gaglio D, Bonfanti R, Tucci FA, Ceccacci E, Pennisi R, Bonanomi M, Jodice G, Tillhon M, Montani F, Bertalot G, Freddi S, Vecchi M, Taglialatela A, Romanenghi M, Romeo F, Bianco N, Munzone E, Sanguedolce F, Vago G, Viale G, Di Fiore PP, Minucci S, Alberghina L, Colleoni M, Veronesi P, Tosoni D, Pece S. Nat Commun. 2022 May 12;13(1):2642. doi: 10.1038/s41467-022-30375-8.
8. Polystyrene micro and nano-particles induce metabolic rewiring in normal human colon cells: A risk factor for human health. Bonanomi M, Salmistraro N, Porro D, Pinsino A, Colangelo AM, Gaglio D. Chemosphere. 2022 Sep;303(Pt 1):134947. doi: 10.1016/j.chemosphere.2022.134947.
9. Transcriptomics and Metabolomics Integration Reveals Redox-Dependent Metabolic Rewiring in Breast Cancer Cells. Bonanomi M, Salmistraro N, Fiscon G, Conte F, Paci P, Bravatà V, Forte GI, Volpari T, Scorza M, Mastroianni F, D’Errico S, Avolio E, Piccialli G, Colangelo AM, Vanoni M, Gaglio D, Alberghina L. Cancers (Basel). 2021 Oct 9;13(20):5058. doi: 10.3390/cancers13205058.
10. Two high-rate pentose-phosphate pathways in cancer cells. Cossu V, Bonanomi M, Bauckneht M, Ravera S, Righi N, Miceli A, Morbelli S, Orengo AM, Piccioli P, Bruno S, Gaglio D, Sambuceti G, Marini C. Sci Rep. 2020 Dec 17;10(1):22111. doi: 10.1038/s41598-020-79185-2.